Abstract
2316
Objectives Evaluation of gynecologic malignancy may be complicated by FDG accumulation in urinary bladder. The purpose of this study was to compare the effect of foley catheter placement on bladder activity in cervical cancer patients undergoing F-18 FDG PET/CT.
Methods 34 patients with cervical cancer were studied. In group A (n=20), a foley catheter (12 or 14 French) with collection bag was placed in the urinary bladder before FDG injection and throughout the scan. In group B (n=14), the patients did not receive foley catheter placement. F-18 FDG PET/CT was performed 60 minutes after intravenous administration of 370MBq F-18 FDG. Maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), total count, total area in pixel, largest diameter and largest anteroposterior length of urinary bladder were calculated. T-test was used to compare between these 2 groups. A p-value of less than 0.05 was considered as statistically significant.
Results These 2 groups were comparable in age, body weight, body height, blood glucose level and serum creatinine level. The mean SUVmax, mean SUVmean, mean total count, mean total area, mean diameter and mean anteroposterior length in group A patients were 47.3, 8.9, 17032, 1165, 7.2cm and 4.6cm respectively, and those in group B patients were 52, 11.6, 19373, 1331, 8.0cm and 5.6cm respectively. The anteroposterior length in group A was significantly lower (p=0.019) than in group B. But there was no significant difference in mean SUVmax, mean SUVmean, mean total count, mean area and mean diameter between group A and group B.
Conclusions Our study showed that foley catheter placement during PET/CT scanning reduced the anteroposterior length of urinary bladder but it did not reduce bladder activity. Thus, foley catheter placement alone may not effective in eliminating image artifacts of urinary bladder in gynecologic malignancy