^99mTc-fucoidan has been found to be a relevant imaging agent for in vivo detection of biologic activities associated with P-selectin overexpression, such as arterial thrombus and ischemic memory, and overcomes some limitations of previous P-selectin–targeted agents. In the above SPECT/CT slices of a rat with aortic valve endocarditis, ^99mTc-fucoidan uptake is seen in the aortic valve area.
See page 1433.