Time-of-flight PET significantly improves observer performance in detecting focal lesions on a noisy background, as illustrated by this ¹⁸F-FDG PET/CT scan of a patient with esophageal cancer and a body mass index of 27. The reconstructions that include time-of-flight information show improved uniformity in the liver and mediastinal region and better delineate the bone marrow in the ribs and spine.
See page 1315.