Article Figures & Data
Figures
- FIGURE 1.
Acquisition protocol schematic showing interleaving of 2D and 3D acquisitions for each bed position.
- FIGURE 2.
Representative PET images of whole-body phantom corresponding to acquisitions of 2 min per bed position (coronal view [left] and sagittal view [right]). Horizontal lines indicate limits of different bed positions. Note bed overlap seen between first 2 bed positions.
- FIGURE 3.
Comparison of 2D and 3D count rates for brain (A and B), thorax (C and D), and abdomen (E and F) as function of mean activity concentration in phantom thoracic chamber.
- FIGURE 4.
Comparison of 2D and 3D NEC rates in phantom and in entire FOV as function of activity concentration in phantom thoracic chamber for brain (A), thorax (B), and abdomen (C).
- FIGURE 5.
Variations of 2D and 3D prompt and random coincidence rates as function of single-photon rates for bed positions centered on thorax (A and C) and abdomen (B and D) for phantom and clinical datasets.
- FIGURE 6.
Linear regressions for single-photon rates in 3D mode as function of mean dose in patient at scan start for acquisitions centered on thorax and abdomen. Dose is normalized by weight (A and C) and by weight corrected for relative BMI (B and D).
- FIGURE 7.
Estimated 2D and 3D NEC as function of dose injected to 170-cm and 70-kg patient assuming 90-min uptake period. These curves were obtained for thorax (A) and abdomen (B).
- FIGURE 8.
Injection rule for 3D acquisition centered on thorax and abdomen as function of patient BMI to achieve peak 3D NEC rate.
Tables
Symbol Definition T True coincidence count rate (kcps) S Scattered coincidence count rate (kcps) R Random coincidence count rate (kcps) P Prompt coincidence count rate, defined as P = T + S + R D Delayed coincidence rate, defined as D = R σs Scatter fraction, defined as σs = S/(T + S) SP Single-photon count rate (Mcps) NEC Noise equivalent count rate (kcps) A Activity concentration (kBq/mL) in phantom thoracic chamber d Mean tracer activity in patient at acquisition start (MBq) c Mean activity per weight d/w ĉ Mean activity in patient normalized for patient morphology α Proportionality constant in SP = α · A (Eq. 1) β and β̂ Proportionality constant in SP = β · c and SP = β · ĉ (Eqs. 8 and 9) w Patient weight (kg) h Patient height (m) BMI Body mass index, defined as BMI = w/h2 - TABLE 3
Percentage Scatter Fractions for Bed Positions Centered on Main Organs of Interest and for 20-cm-Diameter Cylinder
Acquisition mode Brain Thorax Abdomen Cylinder (Obj) Obj FOV Obj FOV Obj FOV 2D 9 19 14 20 14 20 10 3D 25 32 51 56 45 51 31 Obj = within object; FOV = over entire FOV.
- TABLE 4
Percentage Single-Photon Dead-Times, dtSP, for 3D Acquisitions Centered on Thorax and Abdomen
Acquisition site Parameter A (kBq/mL) 4 8 12 16 20 Thorax SP (Mcps) 5 9 13 17 20 dtSP (%) 0 3 7 11 15 Abdomen SP (Mcps) 7 12 18 22 25 dtSP (%) 0 5 11 16 20 - TABLE 5
Percentage True Coincidence Dead-Times, dtT, for 3D Acquisitions Centered on Thorax and Abdomen
Acquisition site Parameter A (kBq/mL) 4 8 12 16 20 Thorax dtT (%) 0 6 18 30 40 Abdomen dtT (%) 2 18 32 46 62
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