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OtherBrief Communications

Sigma Receptor Scintigraphy with N-[2-(1′-Piperidinyl)Ethyl]-3-123I-Iodo-4-Methoxybenzamide of Patients with Suspected Primary Breast Cancer: First Clinical Results

Vicky Caveliers, Hendrik Everaert, Christy S. John, Tony Lahoutte and Axel Bossuyt
Journal of Nuclear Medicine December 2002, 43 (12) 1647-1649;
Vicky Caveliers
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Hendrik Everaert
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Christy S. John
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Tony Lahoutte
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Axel Bossuyt
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  • FIGURE 1.
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    FIGURE 1.

    P-123I-MBA scintigraphy in 2 patients with primary breast cancer of invasive ductal type. Tumor was localized in laterosuperior quadrant of right breast (A) and left breast (B).

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    FIGURE 2.

    Right (A) and left (B) planar breast images of patient presenting bilateral uptake of P-123I-MBA in superior part of breasts. Focal accumulation in left breast (B) did not correspond to known lesion on mammography and could not be confirmed as malignant after follow-up.

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    TABLE 1

    Patient Characteristics and Scintigraphic Results of Lateral Breast Imaging with P-123I-MBA

    Patient no.Age (y)HistologyLocalizationTumor size (cm)P-123I-MBAT/B ratioEvaluation
    160Invasive ductal carcinomaIEQ L3.0Positive2.23TP
    263Invasive ductal carcinomaSEQ L3.2Positive1.36TP
    376Invasive ductal carcinomaSEQ L5.5NegativeFN
    482Invasive ductal carcinomaSEQ L2.5Positive2.31TP
    573Invasive lobular carcinomaSEQ R2.4Positive2.75TP
    677Invasive ductal carcinoma; fibrocystic diseaseSIQ R1.4Positive1.69TP
    770Invasive ductal carcinomaSEQ R2.5Positive2.28TP
    846Invasive ductal carcinomaSEQ R2.4Positive1.84TP
    Positive2.08FP
    951Invasive lobular carcinoma; fibrocystic diseaseSIQ R4.0NegativeFN
    1044Invasive ductal carcinomaIEQ L4.5Indeterminate
    1163Invasive ductal carcinomaSEQ L4.0Positive1.80TP
    1282AdenitisNegativeTN
    • T/B = tumor-to-background; IEQ = inferoexternal quadrant; TP = true-positive; SEQ = superoexternal quadrant; FN = false-negative; SIQ = superointernal quadrant; FP = false-positive; TN = true-negative.

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Journal of Nuclear Medicine
Vol. 43, Issue 12
December 1, 2002
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Sigma Receptor Scintigraphy with N-[2-(1′-Piperidinyl)Ethyl]-3-123I-Iodo-4-Methoxybenzamide of Patients with Suspected Primary Breast Cancer: First Clinical Results
Vicky Caveliers, Hendrik Everaert, Christy S. John, Tony Lahoutte, Axel Bossuyt
Journal of Nuclear Medicine Dec 2002, 43 (12) 1647-1649;

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Sigma Receptor Scintigraphy with N-[2-(1′-Piperidinyl)Ethyl]-3-123I-Iodo-4-Methoxybenzamide of Patients with Suspected Primary Breast Cancer: First Clinical Results
Vicky Caveliers, Hendrik Everaert, Christy S. John, Tony Lahoutte, Axel Bossuyt
Journal of Nuclear Medicine Dec 2002, 43 (12) 1647-1649;
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