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Research ArticleClinical Investigation

111In-Labeled EGF Is Selectively Radiotoxic to Human Breast Cancer Cells Overexpressing EGFR

Raymond M. Reilly, Reza Kiarash, Ross G. Cameron, Nicole Porlier, Jasbir Sandhu, Richard P. Hill, Katherine Vallis, Aaron Hendler and Jean Gariépy
Journal of Nuclear Medicine March 2000, 41 (3) 429-438;
Raymond M. Reilly
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Reza Kiarash
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Ross G. Cameron
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Nicole Porlier
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Jasbir Sandhu
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Richard P. Hill
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Katherine Vallis
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Aaron Hendler
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Jean Gariépy
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Journal of Nuclear Medicine
Vol. 41, Issue 3
March 1, 2000
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111In-Labeled EGF Is Selectively Radiotoxic to Human Breast Cancer Cells Overexpressing EGFR
Raymond M. Reilly, Reza Kiarash, Ross G. Cameron, Nicole Porlier, Jasbir Sandhu, Richard P. Hill, Katherine Vallis, Aaron Hendler, Jean Gariépy
Journal of Nuclear Medicine Mar 2000, 41 (3) 429-438;

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111In-Labeled EGF Is Selectively Radiotoxic to Human Breast Cancer Cells Overexpressing EGFR
Raymond M. Reilly, Reza Kiarash, Ross G. Cameron, Nicole Porlier, Jasbir Sandhu, Richard P. Hill, Katherine Vallis, Aaron Hendler, Jean Gariépy
Journal of Nuclear Medicine Mar 2000, 41 (3) 429-438;
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  • ErbB-2 Blockade and Prenyltransferase Inhibition Alter Epidermal Growth Factor and Epidermal Growth Factor Receptor Trafficking and Enhance 111In-DTPA-hEGF Auger Electron Radiation Therapy
  • Cellular Dosimetry of 111In Using Monte Carlo N-Particle Computer Code: Comparison with Analytic Methods and Correlation with In Vitro Cytotoxicity
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  • Relationship Between Induction of Phosphorylated H2AX and Survival in Breast Cancer Cells Exposed to 111In-DTPA-hEGF
  • Imaging Epidermal Growth Factor Receptor Expression In vivo: Pharmacokinetic and Biodistribution Characterization of a Bioconjugated Quantum Dot Nanoprobe
  • Epidermal Growth Factor Receptor Inhibition Modulates the Nuclear Localization and Cytotoxicity of the Auger Electron Emitting Radiopharmaceutical 111In-DTPA Human Epidermal Growth Factor
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  • Carbon Nanotubes: Potential Benefits and Risks of Nanotechnology in Nuclear Medicine
  • [Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 Is a Highly Efficient Radiotherapeutic for Glucagon-Like Peptide-1 Receptor-Targeted Therapy for Insulinoma
  • Preclinical Pharmacokinetic, Biodistribution, Toxicology, and Dosimetry Studies of 111In-DTPA-Human Epidermal Growth Factor: An Auger Electron-Emitting Radiotherapeutic Agent for Epidermal Growth Factor Receptor-Positive Breast Cancer
  • Auger Electrons: Lethal, Low Energy, and Coming Soon to a Tumor Cell Nucleus Near You
  • A Kit Formulated Under Good Manufacturing Practices for Labeling Human Epidermal Growth Factor with 111In for Radiotherapeutic Applications
  • Cancer Therapy with Auger Electrons: Are We Almost There?
  • Antitumor Effects and Normal Tissue Toxicity of 111In-Labeled Epidermal Growth Factor Administered to Athymic Mice Bearing Epidermal Growth Factor Receptor-Positive Human Breast Cancer Xenografts
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More in this TOC Section

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  • Response Monitoring in Metastatic Breast Cancer: A Prospective Study Comparing 18F-FDG PET/CT with Conventional CT
  • A Head-to-Head Comparison Between Plasma pTau181 and Tau PET Along the Alzheimer’s Disease Continuum
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