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Research ArticleBasic Science Investigation

Kinetic Analysis of 2-[11C]Thymidine PET Imaging Studies: Validation Studies

David A. Mankoff, Anthony F. Shields, Jeanne M. Link, Michael M. Graham, Mark Muzi, Lanell M. Peterson, Janet F. Eary and Kenneth A. Krohn
Journal of Nuclear Medicine April 1999, 40 (4) 614-624;
David A. Mankoff
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Anthony F. Shields
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Jeanne M. Link
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Michael M. Graham
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Mark Muzi
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Lanell M. Peterson
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Janet F. Eary
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Kenneth A. Krohn
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Journal of Nuclear Medicine
Vol. 40, Issue 4
April 1, 1999
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Kinetic Analysis of 2-[11C]Thymidine PET Imaging Studies: Validation Studies
David A. Mankoff, Anthony F. Shields, Jeanne M. Link, Michael M. Graham, Mark Muzi, Lanell M. Peterson, Janet F. Eary, Kenneth A. Krohn
Journal of Nuclear Medicine Apr 1999, 40 (4) 614-624;

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Kinetic Analysis of 2-[11C]Thymidine PET Imaging Studies: Validation Studies
David A. Mankoff, Anthony F. Shields, Jeanne M. Link, Michael M. Graham, Mark Muzi, Lanell M. Peterson, Janet F. Eary, Kenneth A. Krohn
Journal of Nuclear Medicine Apr 1999, 40 (4) 614-624;
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  • Glioma Proliferation as Assessed by 3'-Fluoro-3'-Deoxy-L-Thymidine Positron Emission Tomography in Patients with Newly Diagnosed High-Grade Glioma
  • Biodistribution and Radiation Dosimetry Estimates of 1-(2'-Deoxy-2'-18F-Fluoro-1-{beta}-D-Arabinofuranosyl)-5-Bromouracil: PET Imaging Studies in Dogs
  • Kinetic Modeling of 3'-Deoxy-3'-Fluorothymidine in Somatic Tumors: Mathematical Studies
  • Selectivity of 18F-FLT and 18F-FDG for Differentiating Tumor from Inflammation in a Rodent Model
  • Monitoring Tumor Cell Proliferation by Targeting DNA Synthetic Processes with Thymidine and Thymidine Analogs
  • 3'-[18F]Fluoro-3'-Deoxythymidine ([18F]-FLT) as Positron Emission Tomography Tracer for Imaging Proliferation in a Murine B-Cell Lymphoma Model and in the Human Disease
  • In Vivo Validation of 3'deoxy-3'-[18F]fluorothymidine ([18F]FLT) as a Proliferation Imaging Tracer in Humans: Correlation of [18F]FLT Uptake by Positron Emission Tomography with Ki-67 Immunohistochemistry and Flow Cytometry in Human Lung Tumors
  • Validation of FLT Uptake as a Measure of Thymidine Kinase-1 Activity in A549 Carcinoma Cells
  • Blocking Catabolism with Eniluracil Enhances PET Studies of 5-[18F]Fluorouracil Pharmacokinetics
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