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Research ArticleNuclear Oncology

Modulation of the Multidrug Resistance P-Glycoprotein: Detection with Technetium-99m-Sestamibi In Vivo

Gary D. Luker, Paula M. Fracasso, Jeffrey Dobkin and David Piwnica-Worms
Journal of Nuclear Medicine March 1997, 38 (3) 369-372;
Gary D. Luker
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Paula M. Fracasso
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Jeffrey Dobkin
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David Piwnica-Worms
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Journal of Nuclear Medicine
Vol. 38, Issue 3
March 1, 1997
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Modulation of the Multidrug Resistance P-Glycoprotein: Detection with Technetium-99m-Sestamibi In Vivo
Gary D. Luker, Paula M. Fracasso, Jeffrey Dobkin, David Piwnica-Worms
Journal of Nuclear Medicine Mar 1997, 38 (3) 369-372;

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Modulation of the Multidrug Resistance P-Glycoprotein: Detection with Technetium-99m-Sestamibi In Vivo
Gary D. Luker, Paula M. Fracasso, Jeffrey Dobkin, David Piwnica-Worms
Journal of Nuclear Medicine Mar 1997, 38 (3) 369-372;
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  • Characterization of a 67Ga/68Ga Radiopharmaceutical for SPECT and PET of MDR1 P-Glycoprotein Transport Activity In Vivo: Validation in Multidrug-Resistant Tumors and at the Blood-Brain Barrier
  • A Phase I/II Study of Infusional Vinblastine with the P-Glycoprotein Antagonist Valspodar (PSC 833) in Renal Cell Carcinoma
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  • Evaluation of Pediatric CNS Malignancies with 99mTc-Methoxyisobutylisonitrile SPECT
  • Phase I and Pharmacokinetic Study of the Novel MDR1 and MRP1 Inhibitor Biricodar Administered Alone and in Combination With Doxorubicin
  • A New in Vivo Method to Study P-Glycoprotein Transport in Tumors and the Blood-Brain Barrier
  • Efflux of Rhodamine From CD56+ Cells as a Surrogate Marker for Reversal of P-Glycoprotein-Mediated Drug Efflux by PSC 833
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