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Research ArticleLaboratory Studies

Fluorodeoxyglucose Uptake in Human Cancer Cell Lines Is Increased by Hypoxia

Anaira C. Clavo, Raya S. Brown and Richard L. Wahl
Journal of Nuclear Medicine September 1995, 36 (9) 1625-1632;
Anaira C. Clavo
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Raya S. Brown
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Richard L. Wahl
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Journal of Nuclear Medicine
Vol. 36, Issue 9
September 1, 1995
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Fluorodeoxyglucose Uptake in Human Cancer Cell Lines Is Increased by Hypoxia
Anaira C. Clavo, Raya S. Brown, Richard L. Wahl
Journal of Nuclear Medicine Sep 1995, 36 (9) 1625-1632;

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Fluorodeoxyglucose Uptake in Human Cancer Cell Lines Is Increased by Hypoxia
Anaira C. Clavo, Raya S. Brown, Richard L. Wahl
Journal of Nuclear Medicine Sep 1995, 36 (9) 1625-1632;
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Cited By...

  • Lactic Acid Accumulation in the Tumor Microenvironment Suppresses 18F-FDG Uptake
  • The Reverse Warburg Effect and 18F-FDG Uptake in Non-Small Cell Lung Cancer A549 in Mice: A Pilot Study
  • Use of Pretreatment Metabolic Tumor Volumes on PET-CT to Predict the Survival of Patients with Squamous Cell Carcinoma of Esophagus Treated by Curative Surgery
  • Tumor Microenvironment-Dependent 18F-FDG, 18F-Fluorothymidine, and 18F-Misonidazole Uptake: A Pilot Study in Mouse Models of Human Non-Small Cell Lung Cancer
  • Hypoxia But Not Inflammation Augments Glucose Uptake in Human Macrophages: Implications for Imaging Atherosclerosis With 18Fluorine-Labeled 2-Deoxy-D-Glucose Positron Emission Tomography
  • Phenotyping of Tumor Biology in Patients by Multimodality Multiparametric Imaging: Relationship of Microcirculation, {alpha}v{beta}3 Expression, and Glucose Metabolism
  • High 18F-FDG Uptake in Microscopic Peritoneal Tumors Requires Physiologic Hypoxia
  • 18F-FDG Uptake in Lung, Breast, and Colon Cancers: Molecular Biology Correlates and Disease Characterization
  • Chemotherapy Response Monitoring of Colorectal Liver Metastases by Dynamic Gd-DTPA-Enhanced MRI Perfusion Parameters and 18F-FDG PET Metabolic Rate
  • Assessing Tumor Hypoxia in Cervical Cancer by PET with 60Cu-Labeled Diacetyl-Bis(N4-Methylthiosemicarbazone)
  • Tumor-Specific Positron Emission Tomography Imaging in Patients: [18F] Fluorodeoxyglucose and Beyond
  • Combining Radioimmunotherapy with Antihypoxia Therapy 2-Deoxy-D-Glucose Results in Reduction of Therapeutic Efficacy
  • Low Efficacy of 18F-FDG PET for Detection of Uveal Malignant Melanoma Compared with 123I-IMP SPECT
  • Biologic Correlates of Intratumoral Heterogeneity in 18F-FDG Distribution with Regional Expression of Glucose Transporters and Hexokinase-II in Experimental Tumor
  • Hypoxia and Glucose Metabolism in Malignant Tumors: Evaluation by [18F]Fluoromisonidazole and [18F]Fluorodeoxyglucose Positron Emission Tomography Imaging
  • Prognostic Model of Pulmonary Adenocarcinoma by Expression Profiling of Eight Genes As Determined by Quantitative Real-Time Reverse Transcriptase Polymerase Chain Reaction
  • Cellular Origin and Molecular Mechanisms of 18F-FDG Uptake: Is There a Contribution of the Endothelium?
  • Analysis of the Regional Uptake of Radiolabeled Deoxyglucose Analogs in Human Tumor Xenografts
  • Enhancing Targeted Radiotherapy by Copper(II)diacetyl- bis(N4-methylthiosemicarbazone) Using 2-Deoxy-D-Glucose
  • 3'-[18F]Fluoro-3'-Deoxythymidine ([18F]-FLT) as Positron Emission Tomography Tracer for Imaging Proliferation in a Murine B-Cell Lymphoma Model and in the Human Disease
  • Effect of Respiratory Gating on Quantifying PET Images of Lung Cancer
  • Standardized Uptake Value of 2-[18F] Fluoro-2-Deoxy-D-Glucose in Predicting Outcome in Head and Neck Carcinomas Treated by Radiotherapy With or Without Chemotherapy
  • Relationship Between Retention Index in Dual-Phase 18F-FDG PET, and Hexokinase-II and Glucose Transporter-1 Expression in Pancreatic Cancer
  • Biologic Correlates of 18Fluorodeoxyglucose Uptake in Human Breast Cancer Measured by Positron Emission Tomography
  • Vascular Endothelial Growth Factor-A165 Induces Progression of Melanoma Brain Metastases without Induction of Sprouting Angiogenesis
  • Imaging of Blood Flow and Hypoxia in Head and Neck Cancer: Initial Evaluation with [15O]H2O and [18F]Fluoroerythronitroimidazole PET
  • Glucose Transporter Glut-1 Expression Correlates with Tumor Hypoxia and Predicts Metastasis-free Survival in Advanced Carcinoma of the Cervix
  • Hypoxia-Induced Increase in FDG Uptake in MCF7 Cells
  • Imaging Brain Tumor Proliferative Activity with [124I]Iododeoxyuridine
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