System L amino acid transport is increased in various types of cancer. The tracer 123I-2-
iodotyrosine (2IT), which is accumulated via system L, could thus serve to allow visualization …

3-123I-Iodo-α-methyl-l-tyrosine (123I-IMT) has been developed for SPECT of amino acid
transport imaging. We examined the isoform selectivity of 125I-IMT transport of the 2 human …

We examined transport of 3-[125I] iodo-α-methyl-L-tyrosine ([125I] IMT) in Xenopus laevis
oocytes co-expressing human L-type amino acid transporter 1 (a component of system L) …

l-3-18F-α-methyl tyrosine (18F-FAMT) has been developed as a PET radiotracer for tumor
imaging. Clinical studies have demonstrated the usefulness of 18F-FAMT PET for the …

Expression of system L amino acid transporters (LAT) is strongly increased in many types of
tumor cells. The purpose of this study was to demonstrate that 18F-labeled amino acids, for …

3‐18F‐l‐α‐methyl‐tyrosine ([18F] FAMT), a PET probe for tumor imaging, has advantages of
high cancer‐specificity and lower physiologic background. FAMT‐PET has been proved …

Abstract O-(2-fluoroethyl)-l-tyrosine (FET) labeled with fluorine-18 is an important and
specific tracer for diagnostics of glioblastoma via positron emission tomography (PET) …

Amino acids are important biologic substrates that play crucial roles in virtually all biologic
processes. These ionic nutrients serve not only as basic modules of proteins and hormones …

Large neutral l-amino acids are substrates of system L amino acid transporters. The level of
one of these, LAT1, is increased in many tumors. Aromatic l-amino acids may also be …

Purpose The purpose of this study was to evaluate the usefulness of L-4-borono-2-18 F-
fluoro-phenylalanine (18 F-FBPA) as a tumor-specific probe, in comparison to 18 F-FDG and …