The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

The electromagnetic spectrum contains different frequency bands useful for medical imaging
and therapy. Short wavelengths (ionizing radiation) are commonly used for radiological and …

Low-light microscopy methods are receiving increased attention as new applications have
emerged. One such application is to allow longitudinal imaging of light-sensitive cells with …

Radiotracers are widely used to track molecular processes, both in vitro and in vivo, with
high sensitivity and specificity. However, most radionuclide detection methods have spatial …

Nuclear medicine uses ionizing radiation for both in vivo diagnosis and therapy. Ionizing
radiation comes from a variety of sources, including x-rays, beam therapy, brachytherapy …

The investigation of molecular uptake and its kinetics in cells is valuable for understanding
the cellular physiological status, the observation of drug interventions, and the development …

Nanotechnology has expanded what can be achieved in our approach to cancer treatment.
The ability to produce and engineer functional nanoparticle formulations to elicit higher …

Purpose Cell-based therapies are showing great promise for a variety of diseases, but
remain hindered by the limited information available regarding the biological fate, migration …

The action of radiopharmaceuticals takes place at the level of cells. However, existing
radionuclide assays can only measure uptake in bulk or in small populations of single cells …

Flow-based cytometry methods are widely used to analyze heterogeneous cell populations.
However, their use for small molecule studies remains limited due to bulky fluorescent labels …