Diagnostic accuracy and safety of 16α-[18F] fluoro-17β-oestradiol PET-CT for the assessment of oestrogen receptor status in recurrent or metastatic lesions in patients …

SY Chae, SH Ahn, SB Kim, S Han, SH Lee… - The Lancet …, 2019 - thelancet.com
Background A biopsy of first recurrence or metastatic disease is recommended to re-evaluate
oestrogen receptor status in patients with breast cancer and to select appropriate treatment…

[HTML][HTML] microRNA-155 positively regulates glucose metabolism via PIK3R1-FOXO3a-cMYC axis in breast cancer

…, JW Lee, HJ Kim, J Kim, H Yoo, HJ Lee, SY Chae… - Oncogene, 2018 - nature.com
MicroRNA is an endogenous, small RNA controlling multiple target genes and playing roles
in various biological processes including tumorigenesis. Here, we addressed the function of …

[HTML][HTML] Comparison of diagnostic sensitivity of [18F]fluoroestradiol and [18F]fluorodeoxyglucose positron emission tomography/computed tomography for breast …

SY Chae, HJ Son, DY Lee, E Shin, JS Oh, SY Seo… - EJNMMI research, 2020 - Springer
Comparison of diagnostic sensitivity of [18F]fluoroestradiol and [18F]fluorodeoxyglucose
positron emission tomography/computed tomography for breast cancer recurrence in patients …

[HTML][HTML] Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks

GH Ha, JH Ji, S Chae, J Park, S Kim, JK Lee… - Nature …, 2019 - nature.com
DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They
rely on highly coordinated processes including posttranslational modifications of proteins. …

A randomized feasibility study of 18F-Fluoroestradiol PET to predict pathologic response to neoadjuvant therapy in estrogen receptor–rich postmenopausal breast …

SY Chae, SB Kim, SH Ahn, HO Kim… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The aim of this study was to explore the ability of 18 F-fluoroestradiol ( 18 F-FES) PET/CT
imaging to predict pathologic response to neoadjuvant therapy in postmenopausal women with …

[HTML][HTML] A phase 1, first-in-human study of 18F-GP1 positron emission tomography for imaging acute arterial thrombosis

SY Chae, TW Kwon, S Jin, SU Kwon, C Sung, SJ Oh… - EJNMMI research, 2019 - Springer
Background 18 F-GP1 is a novel positron emission tomography (PET) tracer that targets
glycoprotein IIb/IIIa receptors on activated platelets. The study objective was to explore the …

Comparison of MRI and PET-CT in detecting the loco-regional recurrence of soft tissue sarcomas during surveillance

SY Park, HW Chung, SY Chae, JS Lee - Skeletal radiology, 2016 - Springer
Objective To investigate the diagnostic performance of MRI and PET-CT for the detection of
loco-regional recurrences after soft tissue sarcoma (STS) excision. Materials and Methods …

Feasibility of dynamic stress 201Tl/rest 99mTc-tetrofosmin single photon emission computed tomography for quantification of myocardial perfusion reserve in …

…, SJ Kang, JS Oh, E Shin, C Sung, SY Chae… - European Journal of …, 2018 - Springer
Purpose We evaluated the feasibility of dynamic stress 201 Tl/rest 99m Tc-tetrofosmin SPECT
imaging using a cardiac camera equipped with cadmium-zinc-telluride detectors for the …

[HTML][HTML] The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation

HS Lee, Z Lin, S Chae, YS Yoo, BG Kim, Y Lee… - Nature …, 2018 - nature.com
Chromatin remodelers regulate the nucleosome barrier during transcription, DNA replication,
and DNA repair. The chromatin remodeler RSF1 is enriched at mitotic centromeres, but the …

USP39 promotes non-homologous end-joining repair by poly (ADP-ribose)-induced liquid demixing

…, S Park, J Yoon, H Yun, JH Ji, S Chae… - Nucleic acids …, 2021 - academic.oup.com
Mutual crosstalk among poly(ADP-ribose) (PAR), activated PAR polymerase 1 (PARP1)
metabolites, and DNA repair machinery has emerged as a key regulatory mechanism of the …