TABLE 3

P Values from Univariate Analysis with Log-Rank Tests for Determining Prognostic Significance of Variables Regarding the 3 Follow-up Endpoints

Variable	Clinical/radiologic tumor progression	Malignant transformation from low- to high-grade glioma	Death due to Disease
Biologic variables
Sex	0.70	0.34	0.69
Age	0.22	0.20	0.28
Age (<40 y/≥40 y)	0.71	0.17	0.95
Seizure history (yes/no)	0.88	0.67	0.013
MRI features
Hemispheric (right/left)	0.87	0.49	0.55
Brain lobe location	0.52	0.61	0.76
Deep/superficial	0.27	0.95	0.06
Circumscribed/diffuse	<0.0001	<0.0001	0.008
Size (<3 cm/≥3 cm)	0.09	0.22	0.44
Mass shift (yes/no)	0.12	0.25	0.04
FET uptake
Mean FET uptake	0.05	0.11	0.10
Mean FET uptake (≤1.1/>1.1)	0.001	0.006	0.06
Maximum FET uptake	0.19	0.43	0.46
Maximum FET uptake (≤2.0/>2.0)	0.50	0.42	0.83
Histologic features
Astrocytoma/oligodendroglioma	0.89	0.96	0.35
Gemistocytic (yes/no)	0.81	0.20	0.58
Mib1	0.48	0.71	0.96
p53	0.49	0.69	0.75
Initial therapy
Cytoreduction/biopsy	0.46	0.78	0.90
Resection (total/subtotal/partial)	0.79	0.82	0.84