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Journal of Nuclear Medicine

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Research ArticleBasic Science Investigation

212Bi-Macroaggregated Albumin Inhibited Mouse Melanoma Growth by Regulating Cell Cycle Checkpoint Markers Without Promoting Living Cell Repopulation

Satyendra Kumar Singh, Nathan Kauffman, Isabelle Maria Lynch, Zeynep Meral Kunt, Kurt R. Zinn, Dalen Agnew and Jinda Fan
Journal of Nuclear Medicine April 2025, jnumed.124.269190; DOI: https://doi.org/10.2967/jnumed.124.269190
Satyendra Kumar Singh
1Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan;
2Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan;
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Nathan Kauffman
1Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan;
2Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan;
3Comparative Medicine and Integrative Biology, Michigan State University, East Lansing, Michigan;
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Isabelle Maria Lynch
1Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan;
2Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan;
3Comparative Medicine and Integrative Biology, Michigan State University, East Lansing, Michigan;
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Zeynep Meral Kunt
2Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan;
4Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan;
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Kurt R. Zinn
1Department of Biomedical Engineering, Michigan State University, East Lansing, Michigan;
2Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan;
3Comparative Medicine and Integrative Biology, Michigan State University, East Lansing, Michigan;
5Department of Radiology, Michigan State University, East Lansing, Michigan;
6Department of Small Animal Clinical Sciences, Michigan State University, East Lansing, Michigan;
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Dalen Agnew
7Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan; and
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Jinda Fan
2Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, Michigan;
5Department of Radiology, Michigan State University, East Lansing, Michigan;
8Department of Chemistry, Michigan State University, East Lansing, Michigan
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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212Bi-Macroaggregated Albumin Inhibited Mouse Melanoma Growth by Regulating Cell Cycle Checkpoint Markers Without Promoting Living Cell Repopulation
Satyendra Kumar Singh, Nathan Kauffman, Isabelle Maria Lynch, Zeynep Meral Kunt, Kurt R. Zinn, Dalen Agnew, Jinda Fan
Journal of Nuclear Medicine Apr 2025, jnumed.124.269190; DOI: 10.2967/jnumed.124.269190

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212Bi-Macroaggregated Albumin Inhibited Mouse Melanoma Growth by Regulating Cell Cycle Checkpoint Markers Without Promoting Living Cell Repopulation
Satyendra Kumar Singh, Nathan Kauffman, Isabelle Maria Lynch, Zeynep Meral Kunt, Kurt R. Zinn, Dalen Agnew, Jinda Fan
Journal of Nuclear Medicine Apr 2025, jnumed.124.269190; DOI: 10.2967/jnumed.124.269190
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Keywords

  • α-particles
  • 212Bi
  • macroaggregated albumin
  • mouse melanoma
  • tumor repopulation
  • epithelial–mesenchymal transition
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