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Journal of Nuclear Medicine

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Research ArticleBasic Science Investigation

[11C]ZTP-1: An Effective Short-Lived Radioligand for PET of Rat and Monkey Brain Phosphodiesterase Type 4 Subtype B

Qunchao Zhao, Jeih-San Liow, Joo Eun Jee, Jose Montero Santamaria, Matilah Pamie-George, Cheryl Morse, Shawn Wu, Sami S. Zoghbi, Sung Won Kim, Robert B. Innis, Victor W. Pike and Sanjay Telu
Journal of Nuclear Medicine May 2025, jnumed.124.269159; DOI: https://doi.org/10.2967/jnumed.124.269159
Qunchao Zhao
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Jeih-San Liow
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Joo Eun Jee
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Jose Montero Santamaria
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Matilah Pamie-George
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Cheryl Morse
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Shawn Wu
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Sami S. Zoghbi
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Sung Won Kim
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Robert B. Innis
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Victor W. Pike
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Sanjay Telu
Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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[11C]ZTP-1: An Effective Short-Lived Radioligand for PET of Rat and Monkey Brain Phosphodiesterase Type 4 Subtype B
Qunchao Zhao, Jeih-San Liow, Joo Eun Jee, Jose Montero Santamaria, Matilah Pamie-George, Cheryl Morse, Shawn Wu, Sami S. Zoghbi, Sung Won Kim, Robert B. Innis, Victor W. Pike, Sanjay Telu
Journal of Nuclear Medicine May 2025, jnumed.124.269159; DOI: 10.2967/jnumed.124.269159

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[11C]ZTP-1: An Effective Short-Lived Radioligand for PET of Rat and Monkey Brain Phosphodiesterase Type 4 Subtype B
Qunchao Zhao, Jeih-San Liow, Joo Eun Jee, Jose Montero Santamaria, Matilah Pamie-George, Cheryl Morse, Shawn Wu, Sami S. Zoghbi, Sung Won Kim, Robert B. Innis, Victor W. Pike, Sanjay Telu
Journal of Nuclear Medicine May 2025, jnumed.124.269159; DOI: 10.2967/jnumed.124.269159
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Keywords

  • PDE4B
  • PET
  • [11C]ZTP-1
  • rat
  • monkey
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