Can 177Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET? Findings from Multicenter Data

Azadeh Akhavanallaf; Zhonglin Lu; Avery B. Peterson; Johan Blakkisrud; Sara Kurkowska; Surekha Yadav; Chang Wang; Carlos Uribe; Caroline Stokke; Arman Rahmim; Ka Kit Wong; Jean-Mathieu Beauregard; Thomas A. Hope; Katarina Sjögreen Gleisner; Yuni K. Dewaraja

doi:10.2967/jnumed.124.269098

Research ArticleTheranostics

Can ¹⁷⁷Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET? Findings from Multicenter Data

Azadeh Akhavanallaf, Zhonglin Lu, Avery B. Peterson, Johan Blakkisrud, Sara Kurkowska, Surekha Yadav, Chang Wang, Carlos Uribe, Caroline Stokke, Arman Rahmim, Ka Kit Wong, Jean-Mathieu Beauregard, Thomas A. Hope, Katarina Sjögreen Gleisner and Yuni K. Dewaraja

Journal of Nuclear Medicine May 2025, jnumed.124.269098; DOI: https://doi.org/10.2967/jnumed.124.269098

Azadeh Akhavanallaf

1Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan;

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Zhonglin Lu

1Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan;

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Avery B. Peterson

1Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan;

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Johan Blakkisrud

2Department of Physics and Computational Radiology, Oslo University Hospital, Oslo, Norway;

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Sara Kurkowska

3Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, British Columbia, Canada;

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Surekha Yadav

4Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California;

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Chang Wang

5Department of Biostatistics, University of Michigan, Ann Arbor, Michigan;

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Carlos Uribe

3Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, British Columbia, Canada;

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Caroline Stokke

2Department of Physics and Computational Radiology, Oslo University Hospital, Oslo, Norway;

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Arman Rahmim

3Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, British Columbia, Canada;

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Ka Kit Wong

1Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan;

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Jean-Mathieu Beauregard

6Nuclear Medicine, Department of Medical Imaging, CHU de Québec-Université Laval, Quebec City, Quebec, Canada; and

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Thomas A. Hope

4Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California;

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Katarina Sjögreen Gleisner

7Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden

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Yuni K. Dewaraja

1Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan;

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Journal of Nuclear Medicine

Vol. 66, Issue 5

May 1, 2025

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Can ¹⁷⁷Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET? Findings from Multicenter Data

Journal of Nuclear Medicine May 2025, jnumed.124.269098; DOI: 10.2967/jnumed.124.269098

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Can ¹⁷⁷Lu-DOTATATE Kidney Absorbed Doses be Predicted from Pretherapy SSTR PET? Findings from Multicenter Data

Journal of Nuclear Medicine May 2025, jnumed.124.269098; DOI: 10.2967/jnumed.124.269098

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Keywords

SSTR PET/CT
177Lu-DOTATATE PRRT
dosimetry
absorbed dose prediction

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