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Research ArticleClinical Investigation

[18F]FDG Metabolic Tumor Volume as a Prognostic Marker in Neuroendocrine Neoplasm: A Multicenter Study

David L. Chan, Aimee Hayes, Ioannis Karfis, Alice Conner, Magdalena Mileva, Elizabeth Bernard, Shaunak Navalkissoor, Gopinath Gnanasekaran, Stephen J. Clarke, Paul J. Roach, Patrick Flamen, Martyn E. Caplin, Nick Pavlakis, Christos Toumpanakis and Dale L. Bailey
Journal of Nuclear Medicine May 2025, jnumed.124.269031; DOI: https://doi.org/10.2967/jnumed.124.269031
David L. Chan
1Medical Oncology Department, ENETS Centre of Excellence, Royal North Shore Hospital, Sydney, New South Wales, Australia;
2Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia;
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Aimee Hayes
3Neuroendocrine Tumour Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom;
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Ioannis Karfis
4Nuclear Medicine Department, Institut Jules Bordet, ENETS Centre of Excellence, Université Libre de Bruxelles, Hôpital Universitaire de Bruxelles, Brussels, Belgium;
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Alice Conner
2Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia;
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Magdalena Mileva
4Nuclear Medicine Department, Institut Jules Bordet, ENETS Centre of Excellence, Université Libre de Bruxelles, Hôpital Universitaire de Bruxelles, Brussels, Belgium;
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Elizabeth Bernard
5Nuclear Medicine Department, ENETS Centre of Excellence, Royal North Shore Hospital, Sydney, New South Wales, Australia; and
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Shaunak Navalkissoor
3Neuroendocrine Tumour Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom;
6Nuclear Medicine Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom
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Gopinath Gnanasekaran
3Neuroendocrine Tumour Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom;
6Nuclear Medicine Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom
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Stephen J. Clarke
1Medical Oncology Department, ENETS Centre of Excellence, Royal North Shore Hospital, Sydney, New South Wales, Australia;
2Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia;
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Paul J. Roach
5Nuclear Medicine Department, ENETS Centre of Excellence, Royal North Shore Hospital, Sydney, New South Wales, Australia; and
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Patrick Flamen
4Nuclear Medicine Department, Institut Jules Bordet, ENETS Centre of Excellence, Université Libre de Bruxelles, Hôpital Universitaire de Bruxelles, Brussels, Belgium;
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Martyn E. Caplin
3Neuroendocrine Tumour Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom;
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Nick Pavlakis
1Medical Oncology Department, ENETS Centre of Excellence, Royal North Shore Hospital, Sydney, New South Wales, Australia;
2Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia;
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Christos Toumpanakis
3Neuroendocrine Tumour Department, ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom;
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Dale L. Bailey
2Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia;
5Nuclear Medicine Department, ENETS Centre of Excellence, Royal North Shore Hospital, Sydney, New South Wales, Australia; and
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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[18F]FDG Metabolic Tumor Volume as a Prognostic Marker in Neuroendocrine Neoplasm: A Multicenter Study
David L. Chan, Aimee Hayes, Ioannis Karfis, Alice Conner, Magdalena Mileva, Elizabeth Bernard, Shaunak Navalkissoor, Gopinath Gnanasekaran, Stephen J. Clarke, Paul J. Roach, Patrick Flamen, Martyn E. Caplin, Nick Pavlakis, Christos Toumpanakis, Dale L. Bailey
Journal of Nuclear Medicine May 2025, jnumed.124.269031; DOI: 10.2967/jnumed.124.269031

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[18F]FDG Metabolic Tumor Volume as a Prognostic Marker in Neuroendocrine Neoplasm: A Multicenter Study
David L. Chan, Aimee Hayes, Ioannis Karfis, Alice Conner, Magdalena Mileva, Elizabeth Bernard, Shaunak Navalkissoor, Gopinath Gnanasekaran, Stephen J. Clarke, Paul J. Roach, Patrick Flamen, Martyn E. Caplin, Nick Pavlakis, Christos Toumpanakis, Dale L. Bailey
Journal of Nuclear Medicine May 2025, jnumed.124.269031; DOI: 10.2967/jnumed.124.269031
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Keywords

  • prognostic biomarker
  • PET imaging
  • [18F]FDG
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