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Journal of Nuclear Medicine

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Research ArticleThe State of the Art

The Role of PSMA PET Parameters as Biomarkers for Response to PSMA-Targeted Radiopharmaceutical Therapy

Vishnu Murthy, Vinicius Ludwig, Andrei Gafita, Thomas A. Hope and Jeremie Calais
Journal of Nuclear Medicine February 2025, jnumed.124.268818; DOI: https://doi.org/10.2967/jnumed.124.268818
Vishnu Murthy
1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California;
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Vinicius Ludwig
1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California;
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Andrei Gafita
2Division of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland;
3Johns Hopkins Theranostics Center, Baltimore, Maryland; and
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Thomas A. Hope
4Department of Radiology and Biomedical Imaging, University of California, San Francisco, California
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Jeremie Calais
1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California;
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Journal of Nuclear Medicine: 66 (5)
Journal of Nuclear Medicine
Vol. 66, Issue 5
May 1, 2025
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The Role of PSMA PET Parameters as Biomarkers for Response to PSMA-Targeted Radiopharmaceutical Therapy
Vishnu Murthy, Vinicius Ludwig, Andrei Gafita, Thomas A. Hope, Jeremie Calais
Journal of Nuclear Medicine Feb 2025, jnumed.124.268818; DOI: 10.2967/jnumed.124.268818

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The Role of PSMA PET Parameters as Biomarkers for Response to PSMA-Targeted Radiopharmaceutical Therapy
Vishnu Murthy, Vinicius Ludwig, Andrei Gafita, Thomas A. Hope, Jeremie Calais
Journal of Nuclear Medicine Feb 2025, jnumed.124.268818; DOI: 10.2967/jnumed.124.268818
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  • Article
    • Abstract
    • BASELINE PSMA PET VISUAL CRITERIA
    • BASELINE PSMA PET WHOLE-BODY QUANTITATIVE PARAMETERS
    • ADDITIONAL VALUE OF BASELINE 18F-FDG PARAMETERS
    • NOMOGRAMS TO PREDICT OUTCOME AFTER PSMA RPT
    • PSMA PET IN RESPONSE EVALUATION
    • CONCLUSION
    • DISCLOSURE
    • Footnotes
    • REFERENCES
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