PET- and CT-Based Imaging Criteria for Response Assessment of Gastroenteropancreatic Neuroendocrine Tumors Under Radiopharmaceutical Therapy

Felix L. Herr; Christian Dascalescu; Matthias P. Fabritius; Gabriel T. Sheikh; Mathias J. Zacherl; Vera Wenter; Lena M. Unterrainer; Matthias Brendel; Adrien Holzgreve; Christoph J. Auernhammer; Christine Spitzweg; Tanja Burkard; Jens Ricke; Maurice M. Heimer; Clemens C. Cyran

doi:10.2967/jnumed.124.268621

Research ArticleClinical Investigation

PET- and CT-Based Imaging Criteria for Response Assessment of Gastroenteropancreatic Neuroendocrine Tumors Under Radiopharmaceutical Therapy

Felix L. Herr, Christian Dascalescu, Matthias P. Fabritius, Gabriel T. Sheikh, Mathias J. Zacherl, Vera Wenter, Lena M. Unterrainer, Matthias Brendel, Adrien Holzgreve, Christoph J. Auernhammer, Christine Spitzweg, Tanja Burkard, Jens Ricke, Maurice M. Heimer and Clemens C. Cyran

Journal of Nuclear Medicine March 2025, jnumed.124.268621; DOI: https://doi.org/10.2967/jnumed.124.268621

Felix L. Herr

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Christian Dascalescu

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Matthias P. Fabritius

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Gabriel T. Sheikh

2Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany;

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Mathias J. Zacherl

2Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany;

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Vera Wenter

2Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany;

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Lena M. Unterrainer

2Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany;

3Bayerisches Zentrum für Krebsforschung, partner site Munich, Munich, Germany;

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Matthias Brendel

2Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany;

4German Center for Neurodegenerative Diseases, Munich, Germany;

5Munich Cluster for Systems Neurology (SyNergy), University of Munich, Munich, Germany;

6German Cancer Consortium, partner site Munich, a partnership between DKFZ and LMU, Munich, Germany;

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Adrien Holzgreve

2Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany;

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Christoph J. Auernhammer

7Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM, ENETS certified Center of Excellence), LMU University Hospital, LMU Munich, Munich, Germany; and

8Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany

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Christine Spitzweg

7Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM, ENETS certified Center of Excellence), LMU University Hospital, LMU Munich, Munich, Germany; and

8Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany

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Tanja Burkard

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Jens Ricke

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Maurice M. Heimer

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Clemens C. Cyran

1Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany;

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Journal of Nuclear Medicine

Vol. 66, Issue 4

April 1, 2025

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PET- and CT-Based Imaging Criteria for Response Assessment of Gastroenteropancreatic Neuroendocrine Tumors Under Radiopharmaceutical Therapy

Journal of Nuclear Medicine Mar 2025, jnumed.124.268621; DOI: 10.2967/jnumed.124.268621

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PET- and CT-Based Imaging Criteria for Response Assessment of Gastroenteropancreatic Neuroendocrine Tumors Under Radiopharmaceutical Therapy

Journal of Nuclear Medicine Mar 2025, jnumed.124.268621; DOI: 10.2967/jnumed.124.268621

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Keywords

GEP-NET
SSTR PET/CT
RPT
response criteria
human studies

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