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FIGURE 9. Two-dimensional PET sinograms and reconstructed transverse images through hot-sphere 18F-filled phantom: sinogram without any perceptible artifacts (A) and corresponding transverse image (B); sinogram with blank diagonal band, suggestive of faulty detector block (C) and corresponding transverse image (D). Despite obvious defect in sinogram C, reconstructed images B and D are virtually indistinguishable. (Courtesy of Dr. Osama Mawlawi, M.D. Anderson Cancer Center, Houston, TX.)