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FIGURE 6. Planar imaging (A) and SPECT/CT (B) performed on patient with active Crohn's disease approximately 45–90 min after injection of autologous 99mTc-HMPAO–labeled leukocytes. Obvious accumulation of radioactivity in terminal ileum is seen on planar imaging. However, SPECT/CT also demonstrates IBD involvement of preterminal ileum, which was obscured on planar imaging because of superimposition with circulating blood pool and with accumulation in underlying bone marrow. (Courtesy of Dr. Paola A. Erba, Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy).
