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FIGURE 2. (A) Sequential static 5-min images of abdominal area recorded at various times after 99mTc-RBC injection. Abnormal accumulation of radioactivity is obvious already in early images (elongated horizontal area in upper abdominal region). Although accumulation of radioactivity increases with time, no obvious progression along intestinal tract is detectable. Localization of bleeding site is equivocal in planar images, being possibly consistent either with transverse colon or with duodenal localization. (B) SPECT/CT images after 99mTc-RBC injection demonstrate that radioactivity accumulation is not localized in anterior abdominal area (as transverse colon would be) but rather in mid region, thus indicating duodenal localization of bleeding. (Courtesy of Dr. Elena Lazzeri, Regional Center of Nuclear Medicine, University of Pisa Medical School, Pisa, Italy.)