JNM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH RSS TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in JNM
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Search for Related Content
Journal of Nuclear Medicine Vol. 49 No. 11 11A-12A
© 2008 by Society of Nuclear Medicine

This Month in JNM

Peptide-based imaging probes: Reubi and Maecke review the basic principles and application of somatostatin-derived, somatostatin-analog, and other emerging tracers for peptide receptors in a range of cancers.
Page 1735
Figure 1

To PIOPED or not to PIOPED: Reinartz provides a critical look at the relationship between the Prospective Investigation of Pulmonary Embolism Diagnosis studies (including data in an article in this issue of JNM) and the decline of ventilation–perfusion scintigraphy.
Page 1739

Perfusion scans and chest radiography: Sostman and colleagues access PIOPED II data and criteria to determine whether perfusion scintigraphy combined with chest radiography but without ventilation scans can offer clinically useful sensitivity and specificity in most patients.
Page 1741

Innovation in neuroimaging: Okumura and colleagues use 18F-fluoroethyl-SPA-RQ, a recently developed PET radioligand, to visualize and quantify the neurokinin 1 receptor in healthy humans and discuss implications for clinical research in psychiatric disorders.
Page 1749
Figure 2

Imaging leukemia with 18F-FLT: Buck and colleagues assess the suitability of this in vivo proliferation marker for visualizing extramedullary sites of acute myeloid leukemia and as a surrogate for disease activity.
Page 1756
Figure 3

H215O PET reproducibility in NSCLC: de Langen and colleagues document the reliability of serial monitoring of tumor perfusion using 15O-labeled water PET in patients with non–small cell lung cancer.
Page 1763
Figure 4

Sentinel node protocol in melanoma: Manca and colleagues detail an approach combining intraoperative node counting with staining, conventional histopathology, and molecular biology techniques for optimal detection of nodal metastases in patients with melanoma.
Page 1769
Figure 5

rhTSH and radiotoxicity: Rosário and colleagues compare recombinant human thyroid-stimulating hormone administration and levothyroxine withdrawal as pretreatments in reducing radiation damage in patients undergoing 131I thyroid remnant ablation.
Page 1776

PET in ENKTL: Suh and colleagues evaluate whether 18F-FDG uptake on pretreatment PET imaging is a predictor of treatment outcomes and survival in patients with extranodal natural killer/T-cell lymphoma of the head and neck.
Page 1783
Figure 6

Figure 7

Global and regional dyssynchrony and SPECT: Van Kriekinge and colleagues apply automatic phase analysis from gated myocardial perfusion SPECT to the characterization of ventricular contraction in patients with left bundle branch block.
Page 1790
Figure 8

Brain SPECT in fibromyalgia: Guedj and colleagues investigate and describe the specific clinical correlates of brain SPECT perfusion abnormalities in patients with fibromyalgia.
Page 1798
Figure 9

Uptake metric reproducibility: Nahmias and Wahl use standard 18F-FDG uptake values on serial PET/CT scans to estimate tumor metabolic activity in patients with various malignant diseases and to assess reproducibility for monitoring treatment efficacy.
Page 1804

90Y-ibritumomab in NHL: Iagaru and colleagues present observations from clinical experience with 90Y-ibritumomab in the radioimmunotherapeutic management of non-Hodgkin's lymphoma.
Page 1809

Surgery, imaging, and hyperparathyroidism: Judson and Shaha provide an educational overview of the role of nuclear medicine techniques in improving outcomes and advancing minimally invasive surgery in primary hyperparathyroidism.
Page 1813
Figure 10

Imaging SSTR2-positive tumors: Wadas and colleagues describe the synthesis, evaluation, and initial small-animal studies of a 64Cu-labeled somatostatin receptor subtype 2 (SSTR2)–selective antagonist with promise for imaging SSTR2-positive tumors.
Page 1819
Figure 11

Expression of an engineered antibody fragment: Wei and colleagues detail a new approach for reporter gene imaging based on cell surface expression of antibody fragments that can irreversibly bind to radiometal chelates.
Page 1828
Figure 12

Imaging reporter genes in MSCs: Roelants and colleagues explore the use of 18F-FHBG PET to image transduced mesenchymal cells infected with adenoviruses and retroviruses carrying the herpes simplex virus type 1 thymidine kinase gene.
Page 1836
Figure 13

Optical imaging of atherosclerotic plaques: Waldeck and colleagues describe in vitro studies using near-infrared fluorescence reflectance techniques to image macrophage-associated {alpha}vβ3 integrin expression.
Page 1845
Figure 14

Transmission scatter in PET: Vandervoort and Sossi investigate the effect of a previously validated method of scatter correction for singles-mode transmission data on quantitative accuracy in small-animal PET.
Page 1852

Hydrophilic 64Cu-ATSM derivative: Bayly and colleagues describe initial biologic experiences with a water-soluble glucose conjugate of the hypoxia tracer 64Cu-ATSM and compare the conjugate with 18F-FDG and 64Cu-ATSM in a rat model of sarcoma.
Page 1862

Adrenomedullin lung imaging: Harel and colleagues report on the development of human adrenomedullin derivatives radiolabeled with 99mTc and on the evaluation of their biodistribution, plasma kinetics, and utility as pulmonary vascular imaging agents.
Page 1869
Figure 15

MR-based PET attenuation correction: Hofmann and colleagues combine local pattern recognition and atlas registration to predict pseudo-CT images from a given MR image and then use the pseudo-CT images for PET attenuation correction.
Page 1875

MIRD Pamphlet No. 20: Wessels and colleagues present the latest in this widely respected dosimetry series, focusing here on strategies for predicting radiation toxicity to the kidneys.
Page 1884

ON THE COVER

In this patient with non-Hodgkin's lymphoma, lesions were seen before therapy on 111In-ibritumomab scanning (left) and 18F-FDG PET (center). Three months after 90Y-ibritumomab treatment, progressive disease was seen on 18F-FDG PET (right). A higher rate of progression despite treatment has been noted in patients with positive findings before therapy, suggesting that patients with bulky disease may require more aggressive management.
Figure 16

See page 1812.


Related articles in JNM:

Peptide-Based Probes for Cancer Imaging
Jean Claude Reubi and Helmut R. Maecke
JNM 2008 49: 1735-1738. [Abstract] [Full Text]  

To PIOPED, or Not to PIOPED
Patrick Reinartz
JNM 2008 49: 1739-1740. [Full Text]  

Sensitivity and Specificity of Perfusion Scintigraphy Combined with Chest Radiography for Acute Pulmonary Embolism in PIOPED II
H. Dirk Sostman, Massimo Miniati, Alexander Gottschalk, Fadi Matta, Paul D. Stein, and Massimo Pistolesi
JNM 2008 49: 1741-1748. [Abstract] [Full Text]  

Quantitative Analysis of NK1 Receptor in the Human Brain Using PET with 18F-FE-SPA-RQ
Masaki Okumura, Ryosuke Arakawa, Hiroshi Ito, Chie Seki, Hidehiko Takahashi, Harumasa Takano, Eisuke Haneda, Ryuji Nakao, Hidenori Suzuki, Kazutoshi Suzuki, Yoshiro Okubo, and Tetsuya Suhara
JNM 2008 49: 1749-1755. [Abstract] [Full Text]  

First Demonstration of Leukemia Imaging with the Proliferation Marker 18F-Fluorodeoxythymidine
Andreas K. Buck, Martin Bommer, Malik E. Juweid, Gerhard Glatting, Stephan Stilgenbauer, Felix M. Mottaghy, Melanie Schulz, Thomas Kull, Donald Bunjes, Peter Möller, Hartmut Döhner, and Sven N. Reske
JNM 2008 49: 1756-1762. [Abstract] [Full Text]  

Reproducibility of Tumor Perfusion Measurements Using 15O-Labeled Water and PET
Adrianus J. de Langen, Mark Lubberink, Ronald Boellaard, Marieke D. Spreeuwenberg, Egbert F. Smit, Otto S. Hoekstra, and Adriaan A. Lammertsma
JNM 2008 49: 1763-1768. [Abstract] [Full Text]  

Optimal Detection of Sentinel Lymph Node Metastases by Intraoperative Radioactive Threshold and Molecular Analysis in Patients with Melanoma
Gianpiero Manca, Antonella Romanini, Daniela Pellegrino, Elisa Borsò, Marianna Rondini, Cinzia Orlandini, Vanna Zucchi, Francesco Pasqualetti, and Giuliano Mariani
JNM 2008 49: 1769-1775. [Abstract] [Full Text]  

Preparation with Recombinant Human Thyroid-Stimulating Hormone for Thyroid Remnant Ablation with 131I Is Associated with Lowered Radiotoxicity
Pedro Weslley Rosário, Michelle Aparecida Ribeiro Borges, and Saulo Purisch
JNM 2008 49: 1776-1782. [Abstract] [Full Text]  

Prognostic Value of Tumor 18F-FDG Uptake in Patients with Untreated Extranodal Natural Killer/T-Cell Lymphomas of the Head and Neck
Cheolwon Suh, Yoon-Koo Kang, Jong-Lyel Roh, Mi Ra Kim, Jae Seung Kim, Jooryung Huh, Jeong Hyun Lee, Yong Ju Jang, and Bong-Jae Lee
JNM 2008 49: 1783-1789. [Abstract] [Full Text]  

Automatic Global and Regional Phase Analysis from Gated Myocardial Perfusion SPECT Imaging: Application to the Characterization of Ventricular Contraction in Patients with Left Bundle Branch Block
Serge D. Van Kriekinge, Hidetaka Nishina, Muneo Ohba, Daniel S. Berman, and Guido Germano
JNM 2008 49: 1790-1797. [Abstract] [Full Text]  

Clinical Correlate of Brain SPECT Perfusion Abnormalities in Fibromyalgia
Eric Guedj, Serge Cammilleri, Jean Niboyet, Patricia Dupont, Eric Vidal, Jean-Pierre Dropinski, and Olivier Mundler
JNM 2008 49: 1798-1803. [Abstract] [Full Text]  

Reproducibility of Standardized Uptake Value Measurements Determined by 18F-FDG PET in Malignant Tumors
Claude Nahmias and Lindi M. Wahl
JNM 2008 49: 1804-1808. [Abstract] [Full Text]  

90Y-Ibritumomab Therapy in Refractory Non-Hodgkin's Lymphoma: Observations from 111In-Ibritumomab Pretreatment Imaging
Andrei Iagaru, Sanjiv Sam Gambhir, and Michael L. Goris
JNM 2008 49: 1809-1812. [Abstract] [Full Text]  

Nuclear Imaging and Minimally Invasive Surgery in the Management of Hyperparathyroidism
Benjamin L. Judson and Ashok R. Shaha
JNM 2008 49: 1813-1818. [Abstract] [Full Text]  

Preparation and Biological Evaluation of 64Cu-CB-TE2A-sst2-ANT, a Somatostatin Antagonist for PET Imaging of Somatostatin Receptor–Positive Tumors
Thaddeus J. Wadas, Martin Eiblmaier, Alexander Zheleznyak, Christopher D. Sherman, Riccardo Ferdani, Kexian Liang, Samuel Achilefu, and Carolyn J. Anderson
JNM 2008 49: 1819-1827. [Abstract] [Full Text]  

Engineered Antibody Fragments with Infinite Affinity as Reporter Genes for PET Imaging
Liu H. Wei, Tove Olafsen, Caius Radu, Isabel J. Hildebrandt, Mark R. McCoy, Michael E. Phelps, Claude Meares, Anna M. Wu, Johannes Czernin, and Wolfgang A. Weber
JNM 2008 49: 1828-1835. [Abstract] [Full Text]  

Comparison Between Adenoviral and Retroviral Vectors for the Transduction of the Thymidine Kinase PET Reporter Gene in Rat Mesenchymal Stem Cells
Véronique Roelants, Daniel Labar, Carole de Meester, Xavier Havaux, Antonio Tabilio, Sanjiv S. Gambhir, Mauro Di Ianni, Anne Bol, Luc Bertrand, and Jean-Louis Vanoverschelde
JNM 2008 49: 1836-1844. [Abstract] [Full Text]  

Fluorescence Reflectance Imaging of Macrophage-Rich Atherosclerotic Plaques Using an {alpha}vβ3 Integrin–Targeted Fluorochrome
Jens Waldeck, Florian Häger, Carsten Höltke, Christian Lanckohr, Angelika von Wallbrunn, Giovanni Torsello, Walter Heindel, Gregor Theilmeier, Michael Schäfers, and Christoph Bremer
JNM 2008 49: 1845-1851. [Abstract] [Full Text]  

Impact of Contamination from Scattered Photons in Singles-Mode Transmission Data on Quantitative Small-Animal PET Imaging
Eric Vandervoort and Vesna Sossi
JNM 2008 49: 1852-1861. [Abstract] [Full Text]  

In Vitro and In Vivo Evaluations of a Hydrophilic 64Cu-Bis(Thiosemicarbazonato)–Glucose Conjugate for Hypoxia Imaging
Simon R. Bayly, Robert C. King, Davina J. Honess, Peter J. Barnard, Helen M. Betts, Jason P. Holland, Rebekka Hueting, Paul D. Bonnitcha, Jonathan R. Dilworth, Franklin I. Aigbirhio, and Martin Christlieb
JNM 2008 49: 1862-1868. [Abstract] [Full Text]  

Use of Adrenomedullin Derivatives for Molecular Imaging of Pulmonary Circulation
François Harel, Yan Fu, Quang Trinh Nguyen, Myriam Letourneau, Louis P. Perrault, Alexandre Caron, Alain Fournier, and Jocelyn Dupuis
JNM 2008 49: 1869-1874. [Abstract] [Full Text]  

MRI-Based Attenuation Correction for PET/MRI: A Novel Approach Combining Pattern Recognition and Atlas Registration
Matthias Hofmann, Florian Steinke, Verena Scheel, Guillaume Charpiat, Jason Farquhar, Philip Aschoff, Michael Brady, Bernhard Schölkopf, and Bernd J. Pichler
JNM 2008 49: 1875-1883. [Abstract] [Full Text]  

MIRD Pamphlet No. 20: The Effect of Model Assumptions on Kidney Dosimetry and Response—Implications for Radionuclide Therapy
Barry W. Wessels, Mark W. Konijnenberg, Roger G. Dale, Hazel B. Breitz, Marta Cremonesi, Ruby F. Meredith, Alan J. Green, Lionel G. Bouchet, A. Bertrand Brill, Wesley E. Bolch, George Sgouros, and Stephen R. Thomas
JNM 2008 49: 1884-1899. [Abstract] [Full Text]  




This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in JNM
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Search for Related Content

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH RSS TABLE OF CONTENTS
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY THE JOURNAL OF NUCLEAR MEDICINE