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FIGURE 2. Statistical image analysis for 78-y-old woman with amnestic MCI. (A) Brain perfusion SPECT data were analyzed with z score mapping system. Specific VOI for very early AD (bilateral posterior cingulate gyri and precunei and parietal association cortex) is demarcated by red lines on MRI template. Significantly decreased rCBF above z score of 2 was observed within this specific VOI (arrows). (B) Gray matter images extracted from MR images were analyzed with z score mapping system. Specific VOI for very early AD (bilateral medial temporal areas, including parahippocampal gyri and amygdaloid bodies) is demarcated by pink sections on MRI template. Significantly decreased gray matter concentration above z score of 2 was observed within this specific VOI (arrows).
