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FIGURE 2. Whole-body PET/CT in 65-y-old man who received irradiation of primary tumor in upper segment of esophagus and regional lymph nodes in supraclavicular and upper mediastinal area. PET/CT displayed multifocal recurrence. (A) Increased 18F-FDG accumulation remained at primary tumor site (SUV = 6.1), indicating tumor residual disease. (B) Mild focal uptake exhibited in a supraclavicular lymph node with a minor SUV of 2.1. This lesion was subsequently confirmed as malignant by biopsy. (C) Area of abnormally increased uptake was also visible at a left paratracheal lymph node (SUV = 7.8), which proved to be metastatic on follow-up.