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FIGURE 2. Representative case of SPECT/CT misalignment before (A) and after (B) reregistration. Stress and rest short-axis slices and polar maps are displayed on left. (A) Noncorrected images (NC) show decreased radiotracer uptake in inferior wall, compared with attenuation-corrected images (AC). Inferior wall uptake is improved, suggesting attenuation artifact on noncorrected images. Anterior wall, however, shows reduced uptake on attenuation-corrected vs. noncorrected images. Significant misalignment of SPECT and CT is shown in fusion images on right. (B) After best possible realignment (right), tracer distribution in attenuation-corrected images at stress and rest is homogeneous (left). AC-R = attenuation-corrected images after reregistration.