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FIGURE 4.  Trace ROI analysis in a single patient (patient 12). Pixelwise profiles of ¹⁸F-FET uptake () and CBF () span from normal cortex over white matter and tumor. Vertical dashed lines represent tumor borders on MRI (patient 12; Fig. 1C). Increases of tumor CBF (T/Cb ratio > 1.0) are more confined to tumor center. T/Cb ratio increases in this patient at a ratio of approximately 2.1 of ¹⁸F-FET uptake.

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