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FIGURE 1. Coregistration of MRI and PET images: a representative newborn rabbit kit (30 µg/kg of endotoxin) on day 1 of life. (A) T1-weighted MR images. (B) Coregistered images. (C) microPET images. Coregistration was done using markers on a custom-made head holder that is visible on PET and MRI. Red arrows indicate water as marker noted on MR image, and green arrows indicate markers evident on PET scan. Overlap of markers (indicated by yellow arrows) is seen on coregistered images. Because of partial-volume effects, 3D ROIs (indicated by orange dashed lines) were drawn for the whole brain and SUV over time was calculated and compared between groups.
