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FIGURE 1. Pulmonary tracer kinetics in sheep with largest response to smoke (s1) and sheep with smallest response to smoke (s5). (A and D) Mean lung activity calculated as average of all voxels within each lung after intravenous injection of ¹³NN-saline. (B and E) Mean lung activity of ¹⁸F-FDG and concentration of this tracer in blood plasma. (E and F) Patlak plots generated from ¹⁸F-FDG kinetics in C and D. Slope of linear regression of Patlak plots yields ¹⁸F-FDG influx constant K_i.

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