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FIGURE 4. 99mTc-Sestamibi pinhole SPECT images of treated rat 1, 3, 5, and 7 mo after MI and, in center column, dual 111In/99mTc-sestamibi pinhole SPECT images 48 h after transplantation. No clear improvement in perfusion was seen in area that had severe defects before treatment (<50% uptake; black arrow) and where the greatest number of implanted cells had been detected. By contrast, improvement of perfusion was clear in neighboring area that had less severe defects before treatment (white arrows). A = anterior wall; I = inferior wall; L = lateral wall; and S = septal wall.