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FIGURE 1. Evolution of myocardial perfusion, as assessed by sestamibi uptake, in the analyzed segments overall (A), in MI segments only (B), and in MI segments from treated rats only (C). (A) Segments were classified as belonging (circles) or not belonging (squares) to underperfused areas (
70% uptake on pretherapeutic SPECT) and were compared between treated rats (n = 118 [
] and 32 [
]) and untreated rats (n = 95 [
] and 25 [•]). (B) Segments were classified as having (triangles) or not having (diamonds) severe perfusion defects (<60% uptake) before transplantation and were compared between treated rats (n = 19 [
] and 13 [
]) and untreated rats (n = 13 [
] and 12 [
]). (C) Segments were classified as having (triangles) or not having (diamonds) severe perfusion defects (<60% uptake) before transplantation and were compared between rats that had (n = 10 [] and 4 []) and rats that did not have (n = 8 [] and 10 []) early retention of 111In-BMSCs. *P < 0.05 for unpaired comparisons. TT= treated; UT = untreated.
