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FIGURE 5. PET/CT for monitoring response and remission status. After 4 cycles of chemotherapy for peripheral T-cell lymphoma (baseline imaging not shown), PET/CT (A) was negative for active disease, and patient completed 2 more cycles. Two months after therapy completion, worrisome symptoms developed, and PET/CT (B) showed multiple 18F-FDG–avid lymph nodes above and below diaphragm. CT at that time was not definitively abnormal but at 2 mo later showed definitive tumor progression. This case indicates that negative PET after treatment does not mean absence of active tumor and also indicates how PET/CT can be more sensitive than CT for detecting early recurrence. MIP = maximum-intensity projection.
