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FIGURE 3. A 25-y-old woman with bulky mediastinal uptake on PET1 (A, anterior view), who was interpreted as positive visually on PET2 (B, left anterior oblique view). Two residual foci were diagnosed (arrows), scored as extent = 1, intensity = 1 for retrosternal site and extent = 2, intensity = 1 for left hilar site. However, SUVBWmax reduction was measured at 80.7%—that is, above the cutoff value of 65.7%, indicating good early response. Patient remained in complete remission after 36 mo of follow-up.