Click on image to view larger version.
FIGURE 2. Immunostaining of PBBS in normal brain (monoclonal, clone 8D7 [kindly supplied by Dr. Pier Casellas, Department of Immunology–Oncology, Sanofi Synthelabo, Montpellier, France], dilution 1:200). Expression of PBBS is seen in smooth muscle cells of tunica media of medium-sized artery in cerebellar white matter (A) and of small cortical artery of frontal cortex (B). (C) PBBS expression is seen in some cuboidal cells (white arrows) of choroid plexus and in some macrophages in underlying fibrovascular core (black arrow). (D) Ependymal cells show expression of PBBS, which is mainly localized in apical cytoplasm.
