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FIGURE 4. (A and B) In representative rabbit with untreated VX2, coronal PET image (A) shows extensive 18F-FDG uptake (arrow) in VX2, and histopathologic specimen (x400, B) shows tumor cells with high nuclear-to-cytoplasmic ratio and abnormal nuclear morphology. (C and D) In representative rabbit with RFA-treated VX2, CT image before treatment (C) shows round tumor with clear boundary, and CT image immediately after treatment (D), with LeVeen needle still inserted in tumor, shows increased density around tumor.