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FIGURE 5. (A and B) Averages obtained from data of 9 subjects in group A. Total plasma activity (dotted line) and activity corresponding to unmetabolized parent compound (solid line) in plasma are shown as function of time for entire study (A) and for first 40 min after injection (B). (C and D) Data of subject who provided arterial blood samples. Activity corresponding to unmetabolized parent compound in plasma is shown as function of time for venous (solid line) and arterial (dotted line) blood samples for entire study (C) and for first 20 min after injection (D). All values are decay corrected to injection time and normalized with injected activity.