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FIGURE 1. (A) Time course of 11C concentration associated with total plasma, unmetabolized L-[1-11C]-leucine, and L-[1-11C]-leucine in plasma protein. (B) Fraction of unmetabolized free L-[1-11C]-leucine relative to total 11C concentration in plasma fitted with a 3-parameter (offset,
, ß) sigmoidal function. Parameter values that best fit data are reported. Fitted curve explains more than 90% of variance in data.
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