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FIGURE 4. (A) Labeled metabolites detected by HPLC (1 and 2) were more polar than the mother compound ¹¹C-MADAM (3) (based on 4-min sample from one subject). (B) Fraction of detected radioactivity in plasma: 1, 2 and 3 correspond to the 3 peaks in HPLC (mean ± SD, n = 9).

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