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FIGURE 1. Graphic illustration of the concept of test landmarks and validation approach. TE1, TE2, TE3: Transformation fields determined independently by experts 1, 2, and 3, respectively; TA: Transformation field determined using algorithm; CTE1, CTE2, CTE3: Location of a landmark identified in CT image space independently by experts 1, 2, and 3, respectively; CTTEST: Test landmark, calculated as average of (CTE1, CTE2, CTE3); PETEXPERT is calculated as average of (PET1, PET2, PET3).
