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FIGURE 4. (A) Axial HCT and PET data (corrected by HCT) for tumor 1 (patient 1). (B) Corresponding axial ACT and PET data (corrected by ACT). SUV for HCT PET and ACT PET were 2.3 and 3.6, respectively. SUV increased 59.0% from HCT PET to ACT PET. (C) Coronal HCT, HCT PET, and maximum-intensity projection (MIP) of HCT PET data. (D) Coronal ACT, ACT PET, and MIP of ACT PET data. With ACT, there was a significant reduction in breathing artifacts caused by different breathing states during HCT and PET, suggesting that ACT can effectively reduce breathing artifacts and improve quantification of PET data. On each image, crosshair or arrow indicates tumor location. Same tumor can be seen in both ACT and PET data in B but not clear in PET data and not in HCT data in A.
