Click on image to view larger version.

FIGURE 4. (A) Brain regions in which rCBF increases significantly in association with improvement in motor function (motor UPDRS) from pre- to postoperative on-stimulation conditions at 5- and 42-mo follow-up (P < 0.0001, uncorrected). Pre-SMA = rostral part of the supplementary motor area. (B and C) rCBF increases superimposed on normalized T1-weighted MR images and on 3-dimensional brain. (D) Plot of individual rCBF values related to motor improvement for pre-SMA from pre- to postoperative conditions. (E) Relationship between rCBF values in pre-SMA and motor UPDRS scores during course of the study.