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FIGURE 2. Time–activity curves for nonsmokers and smokers for ¹¹C-clorgyline for arterial plasma for the first 5 min after injection corrected for the presence of labeled metabolites (A) and for lungs over a 52-min experimental period (B). Note that smokers have reduced arterial input as well as slower lung clearance of ¹¹C. A similar pattern is seen for ¹¹C-clorgyline-D2 (31). (Adapted with permission of (31).)

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