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FIGURE 5. Examples of curve fitting using monocompartmental model (A) and bicompartmental model (C) for the same representative ROI in a control pig. ${circ}$ , Time–activity curve data points obtained with PET. Continuous lines are fitted data using monocompartmental or bicompartmental model. (B) and (D) Corresponding plots of residuals over time. (E) Extra sum of square analysis for nested models as a way to compare relevance of models.

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