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FIGURE 6. Timeactivity curves of 18F-annexin V uptake in heart (A), liver (B), kidney (C), and urine/urinary bladder (D) in normal rats. Uptake is measured as radioactivity (in becquerels) per organ per kilobecquerel injected. These timeactivity curves were generated from imaging study used to calculate dosimetry data in Table 2 and are based on ROIs drawn over most central (highest uptake) transaxial slice of organ in PET images, except for urinary bladder. Curves begin at time zero with injection of radiotracer. Data points represent values for each of 3 animals, and dotted line represents average of those values.