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FIGURE 2. Time–activity curves for rat liver in 2 different imaging studies. (A) Time–activity curve is shown for liver of each animal imaged in Figure 1. Ratio of 18F-annexin V uptake in liver (treated over control) increased from 1.9 to 8.6 over course of imaging session. (B) Time–activity curves are shown for rat livers in second study, imaged after injection of approximately 44.4 MBq in each animal. Animals were untreated (no Rx), or pretreated for 50 and 150 min with cycloheximide before injection of radiotracer. Ratio of 18F-annexin V uptake in liver increased from 1.25 to 3.0 (50-min treatment) and from 2.2 to 6.5 (150-min treatment); only ratio line for 150-min treatment is shown.
