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FIGURE 2. Timeactivity curves generated from ROIs shown in Figure 1. Initial fast distribution of radiotracer throughout most of the body, with slower accumulation in kidneys, is followed by accumulation in urinary bladder, suggesting that major route of elimination is urinary system. Solid circles indicate activity in ROI as percentage of injected dose. Area under curve is determined by trapezoidal integration of first 3 time points through origin and integration of single exponential fit through final 3 time points. Time points are different in different organs as organs occupy different bed positions. Solid squares and dashed lines indicate decay-corrected timeactivity curve.