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FIGURE 1. Patient with focal HI (patient 3). (A) Abnormal focal increased uptake of radiotracer is visualized in pancreas (P) on coronal and axial projections. Physiologic distribution of radiotracer with higher accumulation in kidneys (K) and urinary bladder (UB) and lower accumulation in liver (L) is also observed. (B) The 5 patients with focal HI forms were submitted to partial pancreatectomy. Abnormal hot spot corresponds to an important agglomeration of proinsulin, snaptophysin, chromogranin A, and AADC in adenoma (x100).
