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FIGURE 2. PET/CT-based exclusion of osteomyelitis and localization of infection to soft-tissue abscess in 43-y-old woman with nonhealing ulcer and cellulitis in lateral aspect of right foot. (A and B) 18F-FDG PET coronal (A) and transaxial (B) images show area of increased 18F-FDG uptake in lateral aspect of mid foot. (C) PET/CT localizes abnormal 18F-FDG uptake to soft tissues. (D) CT shows soft-tissue swelling in same area. Patient underwent local drainage and short course of antimicrobial therapy with good clinical response. No evidence of osteomyelitis was found during a clinical and imaging follow-up of 12 mo.