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FIGURE 1. Sample time-activity curve for the liver (LI) is depicted. Open circles represent measured time points. Solid line is monoexponential fit to data given by expression A(t), where A0 is injected activity, 
eff is effective clearance rate given by (Ln(2)/Tp + Ln(2)/Tb), and fLI is fraction of administered activity in liver, back-extrapolated to injection time. Integral of expression from t = 0 to infinity gives expression shown in box. Residence time (
) may be derived as shown in second box.
