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FIGURE 6. Bias and correlation measures of various simplified methods with ART90. (A) Box plot shows percentage bias in simplified outcome measures relative to ART90 in PCG. Subjects were divided into high-binding (ART90 PCG DVR > 1.8) and low-binding (ART90 PCG DVR < 1.8) groups to determine whether methodologic bias was consistent across the spectrum of PIB retention for all simplified analysis methods. Boxes denote the interquartile range (50% of subjects) and median value (solid line), whereas box whiskers indicate 10th and 90th percentile.
, Individual subject values. (B) Slopes of linear correlations between ART90 and simplified methods. (C) Coefficient of determination (r2) for correlations between ART90 and simplified methods.